In 2007, our company developed PRP from brewer’s yeast through special fermentation. By a series of laboratory test, we found that PRP would non-specifically attach to bacteria cell membrane. Besides, PRP will attach to the gut mucous membrane, release the signaling to immune cells and therefore stimulate the immune reaction. Then, swine husbandry was facing with the unsolvable problem of Rotavirus and Porcine reproductive and respiratory syndrome virus. Thus, our company tried to apply PRP into swine feed, to enhance the swine breeding rate.
Since 2013, S.S. Nutrition cooperated with Dr. Chang in National Chiayi University, to examine the serum antibody (IgG) of the swines fed with PRP. The result showed that there was a better data of the breeding rate and the antibody titration in the used ones than the unused. As a result, Mr. Yu conducted a simultaneous comparison test in Yan’s pig farm in Xiaying district, Tainan. The data that immunoglobulin G (IgG) against PRRSv from the serum of used pigs was negative, said that the pigs seemed never infected. However, the IgG titration of the control group was positive. By this test, we ensured PRP could attached non-specifically to PRRSv and induce immune system of producing IgA to protect swines from virus.
If the hypothesis of the prevention of the PRRS is reasonable, PRP will also be able to prevent the avian influenza, easily-mutated virus. Thus in 2013 winter, Mr. Yu added PRP into the chicken feed. The avian influenza infected the unused chickens. However, PRP-added chickens nearby was fine. 7 days later, the serum antibody in the used chicken was negative. Since 2015, we successively apply into geese and laying hens. The farms whose feed was added with PRP were safe from the avian influenza attack.
In 2016, in order to realize the effect of PRP, Mr. Yu appointed National Pingtung University of Science and Technology and National Defense University to conduct the PRRS virus challenge experiment on swines and the H1N1 virus challenge experiment on mice, respectively. The result showed that the amount of the virus in the serum of the experiment group sharply declined and the one in the serum of the control group increased. Specially, the neutralizing antibody of the PRRSV should emerge within 4 weeks of the initial infection. But, the neutralizing antibody was examined in the experiment group one day after taking PRP. This neutralizing antibody might be produced by the mucosal immunity, which strengthened the prevention effect of PRP.
Because this material can non-specifically attach to antigens, we name it as Pathogenic Recognition Protein, PRP.
Via the PRRS virus and H1N1 virus challenge tests, the result shows that PRP could not only prevent the disease but treat the disease. Nowadays, there are still many unsolvable illnesses. We might apply PRP as the vector, which stimulates the immune system to solve the disease, and develop a new medicine.